Zeb1 ELISA Kit for Mouse(Mus musculus) | EIAab.comZeb1 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Zeb1(Gene name) > Mouse

Zeb1 (Gene name),

Zinc finger E-box-binding homeobox 1 (Protein name ), ZEB1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Zeb1(Tcf8;Zfhx1a;Zfx1a;Zfx1ha);

Protein name:

Zinc finger E-box-binding homeobox 1;

Alternative:

Transcription factor 8(TCF-8);Delta EF1;Zinc finger homeobox protein 1a(MEB1);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts (via N-terminus) with SMARCA4/BRG1.

Function:

Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1 (By similarity). Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

1117

Sequence:

50:

100:

150:

200:

250:

300:

350:

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650:

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750:

800:

850:

900:

950:

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1050:

1100:

1117:

ESESESEQLS | EEKTNEA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q64318

KEGG:

mmu:21417

Pfam:

PF05605

Pfam:

PF00096

UniGene:

Mm.3929

SMR:

Q64318

Uniprot:

Q64318

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ELISA Kit for Mouse Zinc finger E-box-binding homeobox 1

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ELISA Kit for Mouse Zinc finger E-box-binding homeobox 1

Cat.:

E14970h

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Manual:

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96T

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ELISA Kit for Mouse Zinc finger E-box-binding homeobox 1

MSDS:

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ELISA Kit for Mouse Zinc finger E-box-binding homeobox 1

Cat.:

E14970m

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Manual:

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96T

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CLIA Kit for Mouse Zinc finger E-box-binding homeobox 1

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CLIA Kit for Mouse Zinc finger E-box-binding homeobox 1

MSDS:

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CLIA Kit for Mouse Zinc finger E-box-binding homeobox 1

Cat.:

U14970m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Zinc finger E-box-binding homeobox 1

Cat.:

U14970h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Mouse Zinc finger E-box-binding homeobox 1

Monoclonal Antibody for Mouse Zinc finger E-box-binding homeobox 1

Protein for Mouse Zinc finger E-box-binding homeobox 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Organization of the gene encoding transcriptional repressor deltaEF1 and cross-species conservation of its domains."
Sekido R. , Takagi T. , Okanami M. , Moribe H. , Yamamura M. , Higashi Y. , Kondoh H.
Gene173:227-232(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6.
tissue: Embryo.
2.

Wu Y. , Montoya G.D. , Rubin S.E. , Brodie S.G. , Jenkins N. , Williams T.M.
Submitted (1995-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
tissue: Spleen.
3.

"Cloning of a cDNA encoding a mouse transcriptional repressor displaying striking sequence conservation across vertebrates."
Genetta T. , Kadesch T.
Gene169:289-290(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Brain.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
5.

"The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs."
Wellner U. , Schubert J. , Burk U.C. , Schmalhofer O. , Zhu F. , Sonntag A. , Waldvogel B. , Vannier C. , Darling D. , zur Hausen A. , Brunton V.G. , Morton J. , Sansom O. , Schuler J. , Stemmler M.P. , Herzberger C. , Hopt U. , Keck T. , more...
Nat. Cell Biol.11:1487-1495(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
6.

"Transcriptional inhibition of REST by NeuroD2 during neuronal differentiation."
Ravanpay A.C. , Hansen S.J. , Olson J.M.
Mol. Cell. Neurosci.44:178-189(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DNA-BINDING;INDUCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY

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